Can odrive work with external hard drive?

I am using paid version of Amazon could drive and 256GB Macbook. I want to sync all my contents (photos, videos) to Amazon cloud drive. I use my SSD disk as my 1st level cache of content on cloud, and it only stores a few recently used ones. I also have a 2T external drive which stores all my contents (service as the 2nd cache of my cloud, or sync all content on the cloud). Can odrive support feature? I currently have to keep switching odrive folders between SDD and external drives. If odrive could support it natively, it can be perfect.

Hi. Thanks for reaching out. Can you tell me a little more about how you are switching odrive folders? I just want to make sure I understand the current process.